CSW Dinner Meeting: 11/16

On Thursday, November 16th, the November CSW meeting will be held at ACS Headquarters, featuring a presentation by Dr. Eugene Mazzola. Logistics can be found below.

Biography: Dr. Eugene Mazzola

Eugene P. Mazzola was born on Feb. 2, 1942 in Montclair, New Jersey.  He obtained an A.B. degree in 1964 from Franklin and Marshall College in Lancaster, PA and a Ph.D. degree in 1971 in Organic Chemistry from the University of Pittsburgh.  From 1970-72, he was a postdoctoral fellow with Professor Harold Goldwhite at the California State University, Los Angeles, applying NMR spectroscopy to dynamic systems in organophosphorus compounds.  He joined the old Bureau of Foods of the U.S. Food and Drug Administration in Washington, DC in 1972 and took charge
of the Bureau’s NMR Facility in 1973, a position that he held until 2015.

His research has focused primarily on the structural elucidation of natural
product food contaminants and food colorant manufacturing impurities by NMR
spectroscopy.  He has taught numerous NMR courses and workshops and has served
on the Editorial Advisory Board of Magnetic Resonance in Chemistry since 1996.  He
has been a member of the organizing committees of the Washington Area NMR
Group since 1996 and the Small Molecule NMR Conference since 1999.  He is an
Adjunct Professor of Chemistry at the University of Maryland and the Virginia Poly-
technic Institute and State University and co-author of the NMR text, Nuclear
Magnetic Resonance Spectroscopy:  An Introduction to Theory, Applications, and
Experimental Methods

Abstract: Application of a Computer-Assisted Structural Elucidation Program for the Structural Determinations of a new Terpenoid Aldehyde and Two Monosulfated Maitotoxins

Complete and partial structures, respectively, of a novel compound and derivatives of the marine toxin, maitotoxin (MTX) have been elucidated and their 1H and 13C NMR spectra assigned employing a variety of 1- and 2-dimensional NMR techniques.  The Advanced Chemistry Development ACD/Structure Elucidator program was critical for determining both (i) part of the former structure that contained a fused bicyclic system with very few hydrogen atoms, which, in turn, exhibited essentially no discriminating HMBC connectivities throughout that portion of the molecule derivative and (ii) that the 9-sulfo group of MTX is still present in two derivatives, suggesting that they are 40-desulfo congeners of MTX.

Meeting Logistics

Date: Thursday, November 16

Time: 6:00 p.m. social hour, 6:30 p.m. dinner, 7:00 p.m. presentation

Location: ACS Headquarters, Marvel Hall, 1155 16th Street, N.W. – Washington, DC

Menu (Catered by VIPS Catering):  Grilled chicken with artichokes, capers, and tomatoes, served with home-style mushroom ravioli topped with basil marinara sauce, grilled asparagus spears with lemon oil, garden salad, rolls, and cookies/brownies. Vegetarian Option: Four-cheese vegetarian lasagna, garden salad, garlic bread, and cookies/brownies
Cost: $20 Members / Guests, $10 Students

RSVP by noon on Tuesday, November 14 to [email protected]  or by phone (messages only: 202-659-2650). Please provide the names in your party when you RSVP. The public is invited to attend. You may attend the talk only, but reservations are appreciated.

Parking:  Parking is available in nearby commercial parking garages. Please be aware that garage closing
times vary. Parking is also available on the street after 6:30 pm, but be aware that most parking meters
are in effect until 10:00 pm and may be limited to 2 hours. You should check the individual meters for
details and payment methods as some are no longer coin-operated.

Metro: Blue/Orange/Silver Line: McPherson Square or Farragut West. Red Line: Farragut North.